MESOTHELIOMA VACCINE PROVED SAFE
Selasa, 04 Oktober 2016
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According to a study recently conducted by a cancer research laboratory in the Netherlands, the most recent vaccine for mesothelioma can prevent and treat mesothelioma, a form of cancer that comes from exposure to asbestos. The researchers have tested the vaccine on 10 patients who had been diagnosed with mesothelioma, with all of them showed increased levels of antibodies against the disease and three of them showed that the tumor has decreased in size.
What are the symptoms of mesothelioma cancer?
The study, published in the American Journal of Respiratory and Critical Care Medicine, explains how vaccines work by creating dendritic cells tumor antigens in malignant mesothelioma in the lining fluid in the lungs of patients. Dr. Joachim Aerts, the author of the study and also a lung specialist at the Erasmus Medical Center in Rotterdam, said that approach by using the patient's immune system to attack tumor useful and creating immunity to the disease, compared with conventional radiation or chemotherapy treatments.
How histological mesothelioma?
Dr Aerts said that this is one of the relatively new form of treatment for cancer, called immunotherapy. Mesothelioma vaccine can be used and relatively safe, with few side effects when compared with current treatment methods. He expressed the hope that further study could improve the survival rate of patients with mesothelioma disease. Currently, patients diagnosed with mesothelioma, the prognosis of his life just to stay less than two years.
Patients who have been exposed to asbestos mesothelioma usually do not show symptoms for several years, or even decades after the initial exposure period. At that time, mesothelioma will continue to run metastases in the lungs and seep into other organs. The other side of this study is that the vaccine could be a direct treatment for workers exposed to asbestos.
Although the side effects shown by patients in this study was not as severe as that experienced by patients undergoing chemotherapy or radiation treatments, one of the potential effects from a change of the immune system of patients during immunotherapy. The study noted that patients recover quickly and showed no signs of autoimmune disease related.
The difference between pleural mesothelioma and peritoneal mesothelioma
Dr Aerts noted a potential problem exists on immunosuppressive disorders. He said that the main problem for the treatment of mesothelioma is a tumor creates an environment in the pleural mesothelium which can reduce the effects of the vaccine. He mentioned that the next step in vaccine development is how to provide immunosuppressive around the cancer to improve the effectiveness of treatment.
Dr Aerts and his fellow researchers have conducted a number of tests on the effects on dendritic cells and how they can affect cancer tumors in mice. Previous research suggests that vaccination produces antibodies needed to destroy malignant cells and maintain healthy surrounding tissue to produce specific immunity.
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